Overactive Bladder (OAB) Drink Advice Study

Radboud University Medical Center

Status: Withdrawn

Conditions: Overactive Bladder Syndrome

Treatments: Dietary Supplement: water

Study type: Interventional

Funder types: Other

Identifiers

NCT00982241

OABdrinkstudy

Details and patient eligibility

About

The researchers want to investigate how fluid intake influences the symptoms of OAB. The researchers will recruit 45 patients with OAB and randomize them (blind) in 3 groups (low/normal/high fluid intake). Patients will follow this drink pattern for 2-5 days, while filling in an standard micturation diary for 2 days. This micturation diary is coupled to: collection of multiple urine samples, urine pH measurements, and a Perception of Intensity of Urgency Scale (PPIUS) scoring table. All this is collected by the patients themselves. Urine samples will be analysed for osmolality by the clinical chemistry department.

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• OAB patients

Exclusion criteria

• benign prostatic hyperplasia
• neurogenic detrusor overactivity
• urine tract infection
• anticholinergics
• intravesical botulin toxin
• cardiac failure
• renal insufficiency
• sacral neurostimulation
• percutaneous neurostimulation

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 3 patient groups

normal fluid intake

Active Comparator group

Description:

1500 ml /day (+/- 300 ml) for 2,5 days

Treatment:

Dietary Supplement: water

high fluid intake

Active Comparator group

Description:

2400 ml/day (+/- 300 ml )for 2,5 days

Treatment:

Dietary Supplement: water

low fluid intake

Active Comparator group

Description:

fluid intake 900 ml/day (+/- 300ml) for 2,5 days

Treatment:

Dietary Supplement: water