Overview of Botriomycoma in Children with a Central Line: Epidemiology, Risk Factors, Treatments

Civil Hospices of Lyon

Status: Active, not recruiting

Conditions: Home Parenteral Nutrition; Infection; Intestinal Failure; Antibiotics; Botriomycoma; Central Line; Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT06708689

69HCL23_0638

Details and patient eligibility

About

Botriomycomas are frequent benign tumors in children. Their appearance on the central catheter orifice is a known event in clinical practice, but one that has been little studied. This lesion could lead to changes in pathways and an increase in the number of sepsis events, which would promote thrombosis and thus depletion of venous capital in patients who have been dependent on a central line for many years.

This study is a pilot study which will enable us to better identify the risk factors for the development of such a tumour, and to take stock of the different treatments used and their respective efficacy.

Enrollment: 240 patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• home parenteral nutrition patients
• never diagnosed with an episode of botriomycoma on their central line
• 0 to 18 years of age at diagnosis

Exclusion criteria

• Botriomycoma more than 10 years old at time of data collection (or lack of data)
• Patient over 18 years of age
• Not on home parenteral nutrition patients

Trial design

240 participants in 2 patient groups

Case / patients

Description:

Pediatric patients requiring a long-term central line for home parenteral nutrition: * home parenteral nutrition patients * diagnosed with at least on episode of botriomycoma on their central line * 0 to 18 years of age at diagnosis of botriomycoma

Control

Description:

Pediatric patients requiring a long-term central line for home parenteral nutrition: * home parenteral nutrition patients * never diagnosed with an episode of botriomycoma on their central line * 0 to 18 years of age at diagnosis