Ovulation Triggering 2 Vs 3 Follicles

Ovo Clinic

Status: Completed

Conditions: Infertility

Treatments: Other: Ovulation triggering

Study type: Observational

Funder types: Industry

Identifiers

NCT06290921

3472

Details and patient eligibility

About

Poor responders in in-vitro fertilization (IVF) cycles represent a major challenge for fertility specialists. Although poor responders tend to have sub-optimal fertility treatment outcomes, many of these patients wish to attempt at least one IVF cycle. Traditionally, IVF cycles producing less than 3 to 4 mature follicles (measuring at least 14 mm) have either been cancelled or converted to intra-uterine insemination (IUI) due to the low pregnancy rates associated with these cycles. The minimal number of follicles required to proceed with egg collection is based on clinical experience, having been determined by weighing the probability of implantation and pregnancy versus the risk of not obtaining quality oocytes or reaching embryo transfer when fewer mature follicles are present. This retrospective quality control study aims to compare pregnancy rates in IVF cycles producing 3 follicles measuring 14 mm and more on trigger day, versus 2 or fewer follicles.

Enrollment: 405 patients

Sex: Female

Ages: 18 to 42 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Stimulated IVF cycle at clinique ovo
• Patients with a maximum of 3 mature follicles (≥14mm) on the day of ovulation trigger

Exclusion criteria

• Cycle cancelation due to no follicles
• History of recurrent implantation failure
• Contraindication of ovulation induction medication