Oxaliplatin and 5-FU Based Preoperative Chemoradiation (LARC-RRP)

University of Oslo (UIO)

Status and phase: Completed; Phase 2

Conditions: Rectal Cancer

Treatments: Drug: 5-FU; Drug: Oxaliplatin; Radiation: Preoperative chemoradiation; Drug: Neoadjuvant oxaliplatin; Procedure: Pelvic surgery; Drug: Chemoradiation

Study type: Interventional

Funder types: Other

Identifiers

NCT00278694

S-05059

Eudractnr 2005-000024-16

Details and patient eligibility

About

Oxaliplatin and 5FU based preoperative chemoradiation in rectal cancer.

Full description

Effect of treatment, safety profile and quality of life scorings.

Enrollment: 109 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Rectal cancer

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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109 participants in 1 patient group

Chemoradiation

Experimental group

Description:

Neoadjuvant chemotherapy and chemoradiation

Treatment:

Procedure: Pelvic surgery

Drug: 5-FU

Drug: Oxaliplatin

Drug: Chemoradiation

Drug: Neoadjuvant oxaliplatin

Radiation: Preoperative chemoradiation