Oxidative Stress in Polycystic Ovary Syndrome

Mardin Artuklu University

Status: Completed

Conditions: Oxidative Stress; Polycystic Ovarian Syndrome (PCOS)

Study type: Observational

Funder types: Other

Identifiers

NCT06826625

2020/23-11

Details and patient eligibility

About

The aim of the study was to determine changes in hematological and biochemical parameters and specific oxidative stress markers in patients with PCOS.

Enrollment: 70 patients

Sex: Female

Ages: 20 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

The PCOS group included patients with oligomenorrhea (menstrual period intervals of more than 35 days), clinical signs of hyperandrogenism (acne or hirsutism), biochemical signs of hyperandrogenism (with total testosterone of 100 ng/dL and above and patients with dehydroepiandrosterone sulfate of 400 g/dl and above), an LH/FSH ratio of over 3 on the second day of the menstrual period, a body mass index of 25 and above, and polycystic ovaries detected in suprapubic ultrasonography.

Exclusion criteria

Pregnant individuals, individuals with diabetes mellitus, metabolic syndrome, adrenal pathology, pelvic mass, and malignancy were not included in the study.

Trial design

70 participants in 2 patient groups

polycystic ovary syndrome

Description:

Woman with PCOS

control

Description:

Women without PCOS