Oxycodone Concentration in the Blood After Oral Premedication

Sahlgrenska University Hospital

Status: Completed

Conditions: Oxycontin

Treatments: Drug: Oxycodone

Study type: Observational

Funder types: Other

Identifiers

NCT03386318

Oxycodone premedication

Details and patient eligibility

About

Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy testpersons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg

Full description

Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy test-persons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg 20 female patients between 30 and 60 years will be included after informed consent. They will have day-surgery. The patients will receive 5 mg oxycodone if weighing less than 60 kg and 10 mg if weighing over 60 kg. Serum samples will be taken 1, 2,3,4, and 5 hours after medication intake and serum concentrations will be analyzed

Enrollment: 20 patients

Sex: Female

Ages: 30 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Females <100kg, non-opioid tolerant, day surgery and informed consent

Exclusion criteria

• In complying to inclusion criterias

Trial design

20 participants in 1 patient group

day surgery patients

Description:

20 patients female 30-60 years of age

Treatment:

Drug: Oxycodone