Oxygen Level and Safe Emergence From Anesthesia

Region Västmanland

Status: Completed

Conditions: Focus of Study is Postoperative Pulmonary Atelectacis

Treatments: Procedure: 30% oxygen; Procedure: 100% oxygen

Study type: Interventional

Funder types: Other

Identifiers

NCT01779076

Dnr 2012 / 539

Details and patient eligibility

About

Using a protective ventilation strategy during general anesthesia from pre-oxygenation to emergence and selecting patients without risk of a difficult airway or intubation, a lower fraction of inspiratory oxygen (FIO2) can be used during extubation. This might reduce the postoperative area of atelectasis without desaturations becoming more common.

Enrollment: 59 patients

Sex: All

Ages: 30 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• No sign of difficult airway or intubation
• Day case surgery in total intravenous anesthesia with laryngeal mask airway without adding regional anesthesia of plexus brachialis or muscle relaxant.
• Body mass index less than 35.
• American Society of Anesthesiologists physical status (ASA) class I-III

Exclusion criteria

• Body mass index 35 or higher
• Increased risk of aspiration
• Obstructive sleep apnea syndrome
• Procedures during surgery making a former easy airway a difficult airway
• Need for opioids after extubation
• Hypothermia

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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59 participants in 2 patient groups

100% oxygen during extubation

Experimental group

Description:

In this arm the intervention will consist of 100 % oxygen.

Treatment:

Procedure: 100% oxygen

30% oxygen during extubation

Experimental group

Description:

In this arm the intervention will consist of 30 % oxygen.

Treatment:

Procedure: 30% oxygen