Oxygenation Procedure for Obese Patients During Intubation in the Operating Room (POP-OVNI)

Clinique Pasteur

Status

Not yet enrolling

Conditions

Anesthesia Induction

Treatments

Procedure: NIV (Non Invasive Ventilation) and HFNO (High Flow Nasal Oxygen)

Procedure: NIV (Non Invasive Ventilation)

Study type

Interventional

Funder types

Other

Identifiers

NCT06914401

2024-A02304-43

Details and patient eligibility

About

Obesity is a risk factor for difficult intubation, with an incidence of up to 15.5%, and difficult mask ventilation. Obesity also reduces the functional residual capacity (FRC) of the lungs, the main reservoir of oxygen during apnoea. Complications associated with induction and intubation in the operating room are more frequent in obese patients. Preoxygenation is a cornerstone in the management of patients at risk of desaturation during induction. The study aims to compare two oxygenation strategies , in obese patients. Oxygenation using a combination of NIV (Non Invasive Ventilation) and HFNO (High Flow Nasal Oxygen) compared with NIV alone in the operating room for induction of general anaesthesia with orotracheal intubation.

Enrollment

124 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patient requiring general anaesthesia with orotracheal intubation in the operating room
Obese patient (Body Mass Index , BMI ≥ 30kg/m2)
Patient affiliated to or benefiting from a social security scheme
Patient having signed the free and informed consent form.

Exclusion criteria

Haemodynamic instability
Intubation without laryngoscopy (fibroscope intubation) or nasotracheal intubation
Emergency surgery not allowing patient consent.
Patient with a contraindication to NIV or OHD
Protected patients: Adults under guardianship, curatorship or other legal protection; deprived of liberty by judicial or administrative decision; pregnant, breast-feeding or parturient women; hospitalised without consent.