Oxytocin Effects on Self and Other Processing

University of Electronic Science and Technology of China

Status: Completed

Conditions: Social Behavior

Treatments: Drug: Oxytocin; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT02963194

UESTC-neuSCAN-05

Details and patient eligibility

About

To determine whether the neuropeptide oxytocin (OXT) influences self-processing by investigating whether it increases the endowment effect in relation to both self and others.

Full description

In a double-blind, between- subject placebo (PLC) controlled design, investigator aimed to measure the effect of intranasal OXT on the endowment effect. All subjects completed a range of questionnaires measuring personality and affective traits and levels of anxiety before self-administration: Positive and Negative Affect Schedule (PANAS) , State-Trait Anxiety Inventory (STAI) , Beck Depression Inventory (BDI), self-esteem scale (SES). Subjects were asked to decide whether to buy or sell their own or others' (their mothers'/ fathers'/ classmate'/ strangers') possessions at various prices. Indifference point and brain activation were inluded into analysis as dependent variables.

Enrollment: 44 patients

Sex: Male

Ages: 18 to 27 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

• history of head injury;
• claustrophobia;
• medical or psychiatric illness.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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44 participants in 2 patient groups, including a placebo group

Oxytocin

Experimental group

Description:

Oxytoxin nasal spray

Treatment:

Drug: Oxytocin

Placebo

Placebo Comparator group

Description:

Placebo nasal spray

Treatment:

Drug: Placebo