Oxytocin Effects on the Tolerance of Infidelity

University of Electronic Science and Technology of China

Status: Completed

Conditions: Healthy

Treatments: Drug: placebo treatment; Drug: oxytocin treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT02733237

UESTC-neuSCAN-04

Details and patient eligibility

About

To investigate whether intranasal oxytocin (40 IU) treatment can influence the tolerance of infidelity in males and females.

Full description

In a double-blind, between-subject, placebo controlled design, investigators plan to investigate the effect of oxytocin treatment on the tolerance of infidelity. Male and female subjects would firstly see a neutral face of the opposite sex presented with a sentence descried their fidelity or infidelity behavior (sexual or emotional) in a relationship. Next the participant will rate the attractiveness, likability and trustworthiness of each individual, and whether they would like to have a short/long relationship with him/her. After that there will be some implicit attitude tasks to test their implicit attitude towards potential partners exhibiting previous fidelity or and infidelity.

Enrollment: 160 patients

Sex: All

Ages: 19 to 28 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

• history of head injury;
• pregnant,menstruating,taking oral contraceptives
• medical or psychiatric illness.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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160 participants in 4 patient groups, including a placebo group

male oxytocin group

Experimental group

Description:

male subjects with oxytocin treatment

Treatment:

Drug: oxytocin treatment

female oxytocin group

Experimental group

Description:

female subjects with oxytocin treatment

Treatment:

Drug: oxytocin treatment

male placebo group

Placebo Comparator group

Description:

male subjects with placebo treatment

Treatment:

Drug: placebo treatment

female placebo group

Placebo Comparator group

Description:

female subjects with placebo treatment

Treatment:

Drug: placebo treatment