Oxytocin Infusion and Abdominal Myomectomy

Armed Forces Hospital, Pakistan

Status and phase: Completed; Phase 3

Conditions: Oxytocin and Abdominal Myomectomy

Treatments: Other: oxytocin in abdominal myomectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT03702946

OXYTOCIN

Details and patient eligibility

About

Objective:To compare oxytocin infusion with control, in patients undergoing abdominal myomectomy in terms of mean blood loss.

Design: Single blinded randomized control trial Setting: Obstetrics and Gynecology Department, Military Hospital, Rawalpindi Population: 60 women of ASA class I-II, with intramural fibroids, candidate for elective abdominal myomectomy.

Methods: Women were divided into two groups randomly. In the study group 30 Units of oxytocin in 1000 ml normal saline were given during surgery, at the rate of 15units/hour. In control group, pure normal saline was given.

Main outcome measure: Intra-operative blood loss

Enrollment: 60 patients

Sex: Female

Ages: 25 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. women of ASA class I-II with intramural fibroids,
2. women planned to undergo elective abdominal myomectomy

Exclusion criteria

1. Women with hemoglobin (Hb) < 10g/dl
2. Women with any respiratory or cardiovascular disease.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

study group

Experimental group

Treatment:

Other: oxytocin in abdominal myomectomy

control group

No Intervention group