Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion

Ataturk University

Status and phase: Completed; Phase 4

Conditions: Abortion, Induced; Labor Stage, Third/Drug Effects; Oxytocin/Administration & Dosage; Pregnancy Trimester, Second

Treatments: Drug: Oxytocin

Study type: Interventional

Funder types: Other

Identifiers

NCT02485444

2015-80

Details and patient eligibility

About

This study compares oxytocin infusion to spontaneous follow-up for third-stage of labor at induced mid-trimester abortions. Patients will be randomized to oxytocin infusion or observation with no pharmacologic intervention. Primary outcome of the study is complete abortion rate within two hours of fetal delivery.

Enrollment: 160 patients

Sex: Female

Ages: 17 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

-Women who had mid-trimester termination of pregnancy between 13-24 gestational weeks

Exclusion criteria

• If fetus and placenta expelled together
• Obstetrical haemorrhage needs intervention
• Known prostaglandin allergy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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160 participants in 2 patient groups

Oxytocin

Active Comparator group

Treatment:

Drug: Oxytocin

Observation

No Intervention group