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Oxytocin's Effects on Face Attentional Processing

U

University of Electronic Science and Technology of China

Status

Completed

Conditions

Healthy

Treatments

Drug: oxytocin treatment
Drug: placebo treatment

Study type

Interventional

Funder types

Other

Identifiers

NCT04413786
UESTC-neuSCAN-71

Details and patient eligibility

About

To investigate whether intranasal oxytocin (24IU) treatment has a regulatory effect on attentional processing of emotional faces.

Full description

In a placebo-controlled double-blind between-subject design experiment, investigators plan to investigate the effect of oxytocin treatment on attentional processing of emotional faces. Subjects complete questionnaires in Chinese versions before treatment administration, including the Beck Depression Inventory, Autism Spectrum Quotient , Trait Anxiety Inventory, Toronto Alexithymia Scale, Multidimentional Assessment of Interoceptive Awareness. This experiment consists of two tasks including Emotional Face Cue-target Task and Visual Search Task. In the first task, subjects need to make a response to judge the position of target after a cue-target is presented. In the second task, subjects are asked to search the target "U" or inverted "U" placed on the nose of emotional/neutral faces and make an choices based on their oorientation. During these phases, subjects' response accuracy, response time and electrophysiological activity (ERP) are recorded.

Enrollment

60 patients

Sex

Male

Ages

18 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy subjects without past or current psychiatric or neurological disorders.

Exclusion criteria

  • history of head injury
  • medical or psychiatric illness

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

60 participants in 2 patient groups, including a placebo group

oxytocin group
Experimental group
Description:
male subjects with oxytocin treatment
Treatment:
Drug: oxytocin treatment
placebo group
Placebo Comparator group
Description:
male subjects with placebo treatment
Treatment:
Drug: placebo treatment

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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