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Ozonated Gel and Titanium Platelet-rich Fibrin (on Palatal Wound Healing

A

Alexandria University

Status

Completed

Conditions

Palatal Lesion

Treatments

Other: Conventional treatment
Other: Ozonated Gel Application
Other: T-PRF Application

Study type

Interventional

Funder types

Other

Identifiers

NCT07320391
0968_ 09/2024

Details and patient eligibility

About

Background: autogenous soft tissue grafts can be considered the gold standard for treatment of mucogingival problems. The most common site for harvesting the graft is the palate. The palatal donor site for free gingival graft (FGG) significantly influences the pain and discomfort experienced by the patient, and there is a potential for postoperative bleeding.To overcome these problems many dressing materials associated with topical formulae have been used.

Aim: The objective of this study is to assess the effect of topically applied ozonated oil on palatal wound healing and compare it to the effect of titanium platelet rich fibrin (TPRF)

Enrollment

39 patients

Sex

All

Ages

20 to 50 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Isolated gingival recession defects on the mandibular and maxillary anterior teeth with insufficient keratinized gingiva.
  • Good oral hygiene

Exclusion criteria

  • Patients reporting systemic conditions that may compromise healing or bone metabolism
  • Patients having a history of radiotherapy, chemotherapy or bisphosphonate therapy.
  • Pregnant women or those planning to get pregnant during the study course
  • History of periodontal disease or previous periodontal surgery on the experimental sites
  • Smoking or any other deleterious habits.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

39 participants in 3 patient groups

ozonated gel
Experimental group
Treatment:
Other: Ozonated Gel Application
Application of TPRF
Active Comparator group
Treatment:
Other: T-PRF Application
flowable composite
Other group
Treatment:
Other: Conventional treatment

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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