Ozone Application Before Fissure Sealants

IRCCS Burlo Garofolo

Status: Enrolling

Conditions: Caries,Dental

Treatments: Other: Pits and fissure sealants; Device: Ozone

Study type: Interventional

Funder types: Other

Identifiers

NCT04040920

RC 02/2019

Details and patient eligibility

About

Decay is a multifactorial infective degenerative disease of hard dental tissues, caused by Streptococcus mutans and Lactobacillus forming the bacterial biofilm of teeth surfaces. Decays generally evolve in fissures and pits of secondary molars. Pits and fissure sealants prevent decays if performed in two years from eruption. Ozone has bactericidal effect and remineralizing capacity on enamel.

The aim of this study is to assess the effectiveness of ozone application before sealants in increasing their duration in time.

Enrollment: 67 estimated patients

Sex: All

Ages: 6 to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• first or second secondary molars to be sealed
• possibility to isolate with rubber dam both the teeth involved
• no clear signs of pigmentations
• good general health

Exclusion criteria

• latex allergy
• epilepsy or other severe neurological pathologies
• psychiatric disease
• excessive sensibility to electrical current
• severe asthma
• enamel disorders, such as amelogenesis imperfect, white spots, fluorosis or Molar Incisors Hypomineralization

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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67 participants in 2 patient groups

Ozone therapy

Experimental group

Description:

Ozone application before pits and fissure sealants

Treatment:

Device: Ozone

Other: Pits and fissure sealants

Pits and fissure sealants

Active Comparator group

Treatment:

Other: Pits and fissure sealants