Ozone Gel Application in Controlled Type 2 Diabetic Patients With Periodontitis

Cairo University (CU)

Status: Enrolling

Conditions: Periodontal Diseases

Treatments: Drug: Ozone gel

Study type: Interventional

Funder types: Other

Identifiers

NCT05538078

Ghala

Details and patient eligibility

About

The adjunctive topical subgingival application ozone gel creates a great improvements in the clinical, bacteriological and immunological parameters over the gold standard of periodontal pocket treatment alone.

Full description

The aim of this study is to compare the effect of using ozone gel as a locally delivered adjunct to scaling and root planning versus scaling and root planning alone on the clinical parameters in stageIII grade B in periodontitis patients with controlled diabetic patients.

Enrollment: 24 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patient with controlled diabetic type II. (HgA1C <7) (Mori et al., 2021)
2. Adult patients above 18 years old.
3. Patients with stage III and grade B periodontitis.
4. Patients accept 3-months follow-up period (cooperative patients).
5. Patients provide an informed consent

Exclusion criteria

• 1. Presence of prosthetic crowns. 2. Extensive restorations. 3. Periodontal therapy within the last 12 months. 4. Having surgical therapy or undergoing orthodontic treatment. 5. Ongoing drug therapy that might have an impact on the clinical signs and symptoms of periodontitis.

  2. The use of antibiotics or anti-inflammatory drugs 1 month prior to the procedure and till the end of 3 months of follow-up.

  3. Smokers. 8. Pregnant females. 9. Any known allergies

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

intervention

Experimental group

Description:

Ozone gel

Treatment:

Drug: Ozone gel

active comparator

Active Comparator group

Description:

nonsurgical periodontal treatment(scaling)

Treatment:

Drug: Ozone gel