Packing of Perianal Abscess Cavities Trial: A Randomised Multicentre Trial Comparing Packing With Non-packing of the Abscess Cavity (PPAC)

North Western Research Collaborative

Status: Unknown

Conditions: Perianal Abscess

Treatments: Other: Packing of abscess cavity; Other: External dressing

Study type: Interventional

Funder types: NETWORK

Identifiers

NCT01739478

NWRC-PPAC

Details and patient eligibility

About

The aim of this study is to compare the effect of packing and non-packing on the healing rate of perianal abscess cavities. Secondary objectives are to assess quality of life, cost effectiveness and rate of abscess recurrence and fistula-in-ano formation. If there is no difference in time to healing and non-packing is shown to be safe, acceptable to the patient and cost effective, this approach may become more widely accepted.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of acute primary perianal abscess
• Have undergone surgical incision and drainage as an emergency

Exclusion criteria

• The abscess is the sequelae of concurrent disease or trauma
• Fourniers gangrene is suspected
• Unable to give informed consent

Trial design

300 participants in 2 patient groups

Non-packing of abscess cavity

Experimental group

Treatment:

Other: External dressing

Packing of abscess cavity

Other group

Description:

Current practice

Treatment:

Other: External dressing

Other: Packing of abscess cavity