Padua Prediction Score for VTE Risk in Thoracic Surgery Patients (DVT)

Al-Nahrain University

Status: Not yet enrolling

Conditions: VTE (Venous Thromboembolism); DVT - Deep Vein Thrombosis

Study type: Observational

Funder types: Other

Identifiers

NCT06732726

008

UNCOMIRB20241210

Details and patient eligibility

About

The goal of this observational study is to assess the predictive accuracy of the Padua Prediction Score (PPS) for venous thromboembolism (VTE) risk in thoracic surgery patients.

The study aims to answer the following question:

Does the PPS provide a more accurate prediction of VTE risk?

Participants will:

Have their VTE risk assessed using the PPS during their hospital admission.

Full description

Venous thromboembolism (VTE) is a significant cause of morbidity and mortality, comprising conditions like deep vein thrombosis (DVT) and pulmonary embolism (PE). Hospitalized patients are particularly vulnerable to VTE due to factors such as prolonged immobility, surgical procedures, and preexisting comorbidities.

To address this risk, tools like the Padua Prediction Score (PPS) have been developed. PPS is a validated scoring system that uses clinical and demographic criteria to categorize patients as high- or low-risk for VTE, allowing healthcare providers to tailor prophylactic measures accordingly. Although the Padua Prediction Score has been increasingly adopted in various healthcare settings, its applicability in Iraq remains understudied. There is limited local data on the prevalence of VTE, risk assessment practices and adherence to prophylaxis protocols, leaving a clear gap in the literature. This study aims to explore the utility and predictive accuracy of the Padua Prediction Score in the Iraqi healthcare context. By addressing this gap, the findings could help refine VTE prevention strategies, improve resource allocation, and ultimately reduce complications associated with this condition.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who have undergone preoperative Padua Prediction Score assessment.
• Inpatients with a hospital stay over 3 days
• Written informed consent obtained from patients or their legal guardians.
• Availability for postoperative follow-up to assess outcomes like LEVT development or related complications.

Exclusion criteria

• Preexisting LEVT or pulmonary embolism.
• Severe Coagulopathy: Patients with inherited or acquired bleeding disorders (e.g., hemophilia, advanced liver disease).
• receiving any anticoagulation therapy for any reason.
• patients who did not undergo a postoperative D-dimer test.
• Incomplete Data: missing essential clinical or laboratory data.
• Pregnancy: pregnant women or those within six weeks postpartum.
• Noncompliance: Patients unwilling or unable to adhere to study follow-up protocols.