Pain and Sensation After Regional Anesthesia - Pilot Study

Wake Forest University (WFU)

Status: Completed

Conditions: Osteoarthritis, Hip; Anesthesia, Conduction

Study type: Observational

Funder types: Other

Identifiers

NCT03623035

IRB00052579

Details and patient eligibility

About

This study aims to determine spinal resolution and pain levels after the placement of a lumbar plexus block (LPB) and spinal for total hip replacement procedure. This is a pilot study that looks to collect information in order to design a larger, more significant study comparing Quadratus Lumborum blocks (QLB) and Lumbar Plexus blocks.

Full description

The Quadratus Lumborum block (QLB) is a newer regional analgesic technique that may be as effective as Lumbar Plexus blocks (LPB) at providing pain control following direct anterior approach (DAA) hip arthroplasty. The purpose of this study is to collect pilot data to help the design of a future randomized study, comparing a QLB to a LPB for DAA procedures. The investigators will assess for spinal resolution below the level of L5/S1 by assessing the presence of pin prick sensation at these levels. This will help determine if pain scores collected at 6hrs reflect analgesia provided by the preoperative LPB alone or if the data is confounded by the presence of spinal anesthesia. This data will help us determine if 6hrs is a feasible primary endpoint to assess pain scores. Additionally, assuming that spinal regression is complete by 6hrs, the VAS pain scores obtained will then be used to perform a power analysis to determine the necessary study size when comparing QLB to LPB for DAA hip arthroplasty.

Enrollment: 10 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients that have elective total hip arthroplasty with DAA at Davie Medical Center.

Exclusion criteria

• Patients will be excluded if they do not receive a lumbar plexus block and spinal anesthesia.
• and/or if they have peripheral neuropathy affecting their feet.

Trial design

10 participants in 1 patient group

Lumbar Plexus block Group

Description:

This group includes participants that received Lumbar Plexus blocks (LPB) as the regional analgesic technique in a direct anterior approach (DAA) Total Hip Arthroplasty.