Pain Control After Minimally Invasive Coronary Artery Bypass Grafting

Gundersen Lutheran Medical Foundation

Status and phase: Terminated; Phase 4

Conditions: Medication Side Effects; Postoperative Pain; Narcotic Requirement

Treatments: Drug: IV acetaminophen

Study type: Interventional

Funder types: Other

Identifiers

NCT01770236

2-12-12-001

Details and patient eligibility

About

The purpose of this study is to compare postoperative pain control after minimally invasive coronary artery bypass grafting for patients who receive an intercostal block (an anesthetic medicine injected in an area under the ribs) in the operating room and IV acetaminophen (Tylenol) to those who receive an intercostal block and On-Q pain pump catheter (a balloon pump attached to 2 small tubes near your procedure site that automatically delivers pain medicine).

Enrollment: 41 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age or older
• Coronary artery disease requiring surgical intervention
• No prior sternotomy
• Creatinine within normal limits (0.60 - 1.10 mg/dL)

Exclusion criteria

• Less than 18 years of age
• Inability to provide consent or complete a written survey
• Previous history of sternotomy
• Contraindications to MICS-CABG or to any of the components of the 2 analgesic regimens

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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41 participants in 2 patient groups

IV acetaminophen

Experimental group

Description:

Patients in this group will receive intraoperative intercostal block + IV acetaminophen (1000 mg every 6 hours for adults and weight-based for any patient under 50 kg)

Treatment:

Drug: IV acetaminophen

On-Q Pain Pump catheter

No Intervention group

Description:

Patients in this group will receive the current standard care which includes an intraoperative intercostal block + On-Q Pain Pump catheter (continuous dosing).