Pain Control of Thoracoscopic Major Pulmonary Resection

Seoul National University

Status: Completed

Conditions: Postoperative Pain

Treatments: Procedure: intravenous patient controlled analgesia; Procedure: Pre-emptive bupivacaine wound infiltration

Study type: Interventional

Funder types: Other

Identifiers

NCT01758809

B-1009-111-015

Details and patient eligibility

About

The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.

Full description

Despite less postoperative pain from Video Assisted Thoracic Surgery (VATS) than thoracotomy, pain is still an important issue in its recovery period. After VATS procedure, intravenous patient controlled analgesia (IV PCA) is being used for pain control. However, the side effects of IV PCA are nausea, vomiting, sleepiness, and urination difficulty which interrupt the early recovery. It is established that pre-emptive local bupivacaine injection is more economical, has almost no side effects, and finally, it is effective for the postoperative 24 hours. The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.

Enrollment: 86 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients that are expected to receive VATS segmenectomy or lobectomy regardless of disease entity

Exclusion criteria

• not done by VATS anatomical resection
• patient does not agree to the study
• postoperative hospital stay exceeds 7 days due to postoperative complications
• existence of preoperative renal insufficiency (Cr > 1.5)
• OT/PT > 120
• history of Lidocaine hypersensitivity

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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86 participants in 2 patient groups

Bupivacaine

Active Comparator group

Treatment:

Procedure: Pre-emptive bupivacaine wound infiltration

Intravenous Patient Controlled Analgesia

Other group

Description:

postoperative pain control with intravenous patient controlled analgesia

Treatment:

Procedure: intravenous patient controlled analgesia