Pain Inhibitory Effects of Other Pain Induced by Mechanical Pressure at Different Intensities

Josue Fernandez Carnero

Status: Completed

Conditions: Healthy

Treatments: Other: Mechanical Conditioning stimulus

Study type: Interventional

Funder types: Other

Identifiers

NCT05730166

MechCPM2

Details and patient eligibility

About

The objective is to estimate the effects on pain thresholds of a painful mechanical stimulus on the upper trapezius at moderate intensity compared to mild intensity or non-painful.

Full description

The mechanical stimulus produced in manual therapy (MT) techniques elicits neurophysiological responses within the peripheral and central nervous system responsible for pain inhibition. Almost all types of MT elicit a neurophysiological response that is associated with the descending pain modulation circuit. But it has not been demonstrated whether this inhibition occurs through a conditioned pain modulation mechanism induced by painful mechanical stimulation that is carried out with manual therapy techniques.

Enrollment: 24 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy male or female between 18 and 65 years
• Free of pain and with no history of chronic pain

Exclusion criteria

• Pregnant or having given birth within the last year

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

---

24 participants in 3 patient groups

Mechanical stimulation at moderate pain intensity

Experimental group

Description:

Mechanical compression is applied with the thumb to the upper trapezius muscle on the non-dominant side at the midpoint between the acromion and C7. The intensity of this will be regulated by the pain it causes the patient, trying to ensure that it is at all times approximately 5/10 on the numerical pain rating scale (NPRS) with 0 being "no pain at all" and 10 being "the worst pain imaginable". The stimulation will be carried out for 2 minutes.

Treatment:

Other: Mechanical Conditioning stimulus

Mechanical stimulation at mild pain intensity

Active Comparator group

Description:

Mechanical compression is applied with the thumb to the upper trapezius muscle on the non-dominant side at the midpoint between the acromion and C7. The intensity of this will be regulated by the pain it causes the patient, trying to ensure that it is at all times approximately 2/10 on the numerical pain rating scale (NPRS) with 0 being "no pain at all" and 10 being "the worst pain imaginable". The stimulation will be carried out for 2 minutes.

Treatment:

Other: Mechanical Conditioning stimulus

Painless mechanical stimulation

Active Comparator group

Description:

Mechanical compression is applied with the thumb to the upper trapezius muscle on the non-dominant side at the midpoint between the acromion and C7. The intensity of this will be regulated by the pain it causes the patient, trying to ensure that it is at all times approximately 0/10 on the numerical pain rating scale (NPRS) with 0 being "no pain at all" and 10 being "the worst pain imaginable". The stimulation will be carried out for 2 minutes.

Treatment:

Other: Mechanical Conditioning stimulus