Pain Levels and Opioid Usage in Three Nerve Block Cohorts in Primary TKA

University of Louisville (UOFL)

Status: Withdrawn

Conditions: Knee Arthropathy

Treatments: Other: preop ACB+IPACK block; Other: preop ACB, followed by Intra-articular block during TKA surgery; Other: preop ACB+IPACK block, followed by Intra-articular block during TKA surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT04292392

20.0132

Details and patient eligibility

About

The primary objective of this study is to compare effect of combined block of ACB (adductor canal block) with IPACK (Interspace between the Popliteal Artery and the Capsule of the posterior Knee) block and/or Intra-articular block in immediate postoperative and early postop rehabilitation and pain management in patients undergoing primary TKA. The secondary objective is to review both in-hospital and post-discharge pain levels and narcotic usage of primary TKAs, with a minimum 6-week postoperative follow-up.

Sex: All

Ages: 22 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patient is indicated for a primary, unilateral TKA secondary to osteoarthritis.
2. Patient age is 22-89 at time of TKA surgery.
3. Patient agrees to participate as a study subject and signs the Informed Consent and Research Authorization document.
4. Patient is able to read and speak English.

Exclusion criteria

1. Patient is under the age of 22 or over the age of 89.
2. Patient's primary diagnosis is not osteoarthritis (e.g. post-traumatic arthritis).
3. Patient is scheduled to undergo a bilateral TKA surgery.
4. Patient is unable to read and speak English.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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0 participants in 3 patient groups

A - ACB + Periarticular Block

Experimental group

Description:

Group A: patient will receive a preop ACB, followed by Intra-articular block during TKA surgery

Treatment:

Other: preop ACB, followed by Intra-articular block during TKA surgery

B - ACB + IPACK Block

Experimental group

Description:

Group B: patient will receive a preop ACB+IPACK block before TKA surgery only

Treatment:

Other: preop ACB+IPACK block

C - ACB + IPACK + Periarticular Block

Experimental group

Description:

Group C: patient will receive a preop ACB+IPACK block, followed by Intra-articular block during TKA surgery

Treatment:

Other: preop ACB+IPACK block, followed by Intra-articular block during TKA surgery