Pain Measured by NRS and EEG in Acute Pulpitis

Cleveland Dental Institute

Status: Enrolling

Conditions: Acute Pulpitis

Treatments: Diagnostic Test: Numerical rate Scale (NRS); Diagnostic Test: Brain wave analysis using electroencephalography (EEG).

Study type: Observational

Funder types: Other

Identifiers

NCT06526572

CDIENDO0007

Details and patient eligibility

About

The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB).

The study aims to achieve this by utilizing a dual approach that combines subjective self-reporting of pain intensity using the Numeric Rating Scale (NRS) with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG).

By integrating these two methods, the study seeks to explore potential correlations between self-reported pain scores and neural responses recorded through EEG, providing insights into the pain experience of this specific patient population.

Ultimately, the goal of the study is to enhance the understanding of pain perception mechanisms in individuals with symptomatic acute pulpitis resistant to IANB and potentially guide the development of more effective and personalized pain management strategies for these patients.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Adults aged [18-50 years]. Clinically diagnosed with symptomatic acute pulpitis based on dental examination and radiographic findings.

Demonstrates resistance to inferior alveolar nerve block (IANB). Willing and able to provide informed consent to participate in the study. Able to communicate effectively in the language used for study procedures.

Exclusion criteria

Individuals with known neurological or psychiatric disorders affecting pain perception.

Pregnant individuals or those breastfeeding at the time of the study. History of severe allergies or adverse reactions to local anesthetics or EEG gel.

Presence of significant medical conditions that may contraindicate dental procedures or EEG recordings.

Individuals taking medications that could significantly affect pain perception (e.g., strong analgesics, sedatives).

Any contraindications for dental procedures or EEG recordings as determined by the study's dental and medical professionals.

Inability to understand and follow study instructions.

Trial design

50 participants in 1 patient group

symptomatic acute pulpitis

Description:

Patients with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB)

Treatment:

Diagnostic Test: Numerical rate Scale (NRS)

Diagnostic Test: Brain wave analysis using electroencephalography (EEG).