Pain Neuroscience Education in Diabetic Neuropathy

Riphah International University

Status: Completed

Conditions: Diabetic Nephropathy; Pain, Neuropathic

Treatments: Other: Conventional Physical therapy; Other: Pain Neuroscience Education

Study type: Interventional

Funder types: Other

Identifiers

NCT04721847

REC/00752 Rameeza Warraich

Details and patient eligibility

About

To determine the effects of Pain Neuroscience Education in Diabetic Neuropathy

Full description

Pain neuroscience education (PNE) has shown to have immediate effects on various clinical signs and symptoms associated with central sensitization. Using a model of (innocuous, noxious and allodynia) PNE can be used in combination with exercise therapy, especially treating patients in which the nervous system has become increasingly hypervigilant. Teaching patients about the neuroscience of pain and lead to healthier and more positive attitudes and beliefs regarding chronic pain. Pain in diabetic neuropathy restrict the activity participation and compromise their quality of life. PNE will be helpful in such patients so decreasing pain can improve their quality of life.

Enrollment: 74 patients

Sex: All

Ages: 50 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• History of diabetic ≥ 5 years
• HbA1C higher and equal to 6.5 %
• Self-completed Leeds Assessment of Neuropathic Symptoms and Signs pain scale (S-LANSS) ≥ 12
• Mini Mental State Examination (MMSE) score ≥ 24

Exclusion criteria

• Known neurological disorder
• Foot ulcers/candidate of amputation
• Hearing impaired

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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74 participants in 2 patient groups

Pain Neuroscience Education

Experimental group

Description:

Pain Neuroscience Education (PNE) sessions. Additionally, treated with Transcutaneous Electrical Nerve Stimulation (TENS), Stretching and Strengthening exercises similar as in control group

Treatment:

Other: Pain Neuroscience Education

Conventional Physical therapy

Active Comparator group

Description:

Control group will be treated by TENS, stretching and strengthening exercises.

Treatment:

Other: Conventional Physical therapy