ClinicalTrials.Veeva

Menu

Pain on Injection of Propofol: a Comparison of Lidocaine and Alkalinized Lidocaine

I

Inonu University

Status and phase

Completed
Phase 4

Conditions

Pain on Injection of Propofol,Lidocaine, Alkalinized Lidocaine

Treatments

Drug: Placebo (for alcalinized lidocaine)
Drug: alkalinized lidocaine
Drug: Lidocaine

Study type

Interventional

Funder types

Other

Identifiers

NCT01773044
ulkü_1

Details and patient eligibility

About

Aim: The aim of this study was to compare the efficacy of pretreatment 0.5 mg/kg lidocaine and 0.5 mg/kg alkalinized lidocaine for prevention of propofol induced pain.

Methods: In this double-blind, placebo controlled study, 300 adults patients ASA I or II, scheduled to undergo elective surgery, were randomly assigned into three groups of 100 each. Group L, recevied 0.05 mL/kg lidocaine (% 2 lidocaine 5 mL + 5 mL SF), Group A, 0.05 mL/kg lidocaine with bicarbonate ( % 2 lidocaine 5 mL + 1 mL %8,4 NaHCO3+ 4 mL SF) and control group received isotonic saline pretreatment in the dorsum of the hand, followed by propofol 30 sec later. A blinded researcher assessed the patient's pain level via a four-point scale.

Enrollment

300 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • undergoing elective surgery

Exclusion criteria

  • allergy to the study drug

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

300 participants in 2 patient groups

alkalinized lidocaine & lidocaine
Active Comparator group
Treatment:
Drug: Lidocaine
Drug: alkalinized lidocaine
alkalinized lidocaine &Placebo
Active Comparator group
Treatment:
Drug: alkalinized lidocaine
Drug: Placebo (for alcalinized lidocaine)

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems