Pain Processing and Pain Reporting in Patients With Alzheimer's Disease

University of Aarhus

Status: Completed

Conditions: Pain

Treatments: Behavioral: Thermal stimulation

Study type: Observational

Funder types: Other

Identifiers

NCT03709238

UAarhus_Susan

Details and patient eligibility

About

The study investigates pain processing and pain reporting in patients with Alzheimers disease compared to healthy participants.

Employing a within-subject design, the study includes patients with Alzheimers disease and healthy participants that are exposed to thermal stimuli. During the test session the facial expressions of the participant are video recorded.

By repeating this on separate test days, the involvement of pain relief and pain increase is investigated.

Enrollment: 47 patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Mild to moderate patients with Alzheimers disease (group 1)
• Healthy participants ( group 2)

Exclusion criteria

• Chronic pain conditions
• Other medical, psychiatric or neurological disorders
• Use of pain-reliving medication 24 hours prior to testing

Trial design

47 participants in 2 patient groups

Alzheimers diseased patients

Description:

Behavioral: Different thermal stimulation. Recording of facial expression during thermal stimulation.

Treatment:

Behavioral: Thermal stimulation

Healthy participants

Description:

Behavioral: Different thermal stimulation. Recording of facial expression during thermal stimulation.

Treatment:

Behavioral: Thermal stimulation