Pain-related Evoked Potentials in Unilateral Peripheral Nerve Injuries

Ruhr University of Bochum

Status: Completed

Conditions: Peripheral Nerve Injuries

Treatments: Diagnostic Test: Nerve conduction studies (NCS); Diagnostic Test: Quantitative Sensory Testing (QST); Diagnostic Test: Pain-related evoked potentials (PREP)

Study type: Observational

Funder types: Other

Identifiers

NCT03082820

PREP2015

Details and patient eligibility

About

The study examines pain-related evoked potentials (PREP) in patients with peripheral nerve injuries. Since previous studies found altered latencies and amplitudes of PREP in generalized polyneuropathies, e. g. HIV-polyneuropathy and fibromyalgia, this study investigates if these alterations are detectable in unilateral peripheral nerve injuries as well.

Enrollment: 64 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Peripheral Nerve Injury

Exclusion criteria

• Polyneuropathy
• Contralateral peripheral nerve injury
• Severe psychiatric disorders
• Disorders affecting central nervous system

Trial design

64 participants in 2 patient groups

Patients

Description:

Pain-related evoked potentials (PREP), Quantitative Sensory Testing (QST) and nerve conduction studies (NCS) were performed with patients with peripheral nerve injury.

Treatment:

Diagnostic Test: Quantitative Sensory Testing (QST)

Diagnostic Test: Nerve conduction studies (NCS)

Diagnostic Test: Pain-related evoked potentials (PREP)

Controls

Description:

Pain-related evoked potentials (PREP) and Quantitative Sensory Testing (QST) were performed with healthy adults.

Treatment:

Diagnostic Test: Quantitative Sensory Testing (QST)

Diagnostic Test: Pain-related evoked potentials (PREP)