Pain Relief and Functional Outcome After Partial Denervation of the Wrist

Karolinska Institute

Status: Completed

Conditions: Wrist Arthritis

Treatments: Procedure: Partial denervation of the wrist joint

Study type: Interventional

Funder types: Other

Identifiers

NCT03378362

Karolinska Institute

Details and patient eligibility

About

Prospective study on the effect of partial wrist denervation (ie combined anterior and posterior interosseous neurectomy) on pain relief on functional outcome in patient with wrist osteoarthritis. The impact of psychological factors on postoperative outcome will be studied.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria

1. Chronic wrist pain (≥6 months) due to posttraumatic arthritis after distal radius fracture or SLAC/SNAC arthritis or arthritis due to Mb Preiser/Mb Kienböck where surgical unloading of the bone isn't possible.
2. Pain is refractory to nonsurgical management such as bracing, corticosteroid injection, oral analgesics, NSAIDs, physiotherapy.

Exclusion criteria

1. Rheumatoid or other inflammatory arthritis.
2. Previous wrist surgery with simultaneous PIN/AIN neurectomy.
3. Simultaneous arthritis or symptomatic instability of the distal radio ulnar (DRU) joint on the ipsilateral side.
4. Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction).
5. Patient's wish for a definite procedure.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 1 patient group

Partial denervation of the wrist joint

Experimental group

Description:

Patients will be operated with a partial denervation of the wrist through a single dorsal approach.

Treatment:

Procedure: Partial denervation of the wrist joint