Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration

Rawalpindi Medical University

Status and phase: Enrolling; Phase 4

Conditions: Local Anesthetic Infiltration; Analgeisa; Laparoscopic Cholecystectomy Surgery

Treatments: Drug: Sub cutaneous administration of local anesthetic; Drug: Intraoperitoneal local anesthetic administration

Study type: Interventional

Funder types: Other

Identifiers

NCT07409688

4726/RTH/RWP

Details and patient eligibility

About

Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain management. This local anesthetic can be administered either within abdominal cavity or at sit of small incisions.

Full description

Laparoscopic cholecystectomy is a minimally invasive surgical procedure involving removal of the gallbladder through multiple small trocar incisions. Compared with open surgery, this approach is associated with reduced postoperative pain, shorter hospital stay, and faster recovery. Despite its minimally invasive nature, postoperative pain remains a significant concern, particularly at port sites and from intraperitoneal irritation. Local anesthetic techniques have been shown to contribute to multimodal analgesia in laparoscopic surgery. Local anesthetic agents may be administered either intraperitoneally or by infiltration at trocar insertion sites to reduce postoperative pain and opioid requirements. However, the optimal route of local anesthetic administration for effective postoperative analgesia following laparoscopic cholecystectomy remains uncertain, warranting further clinical evaluation.

Enrollment: 100 estimated patients

Sex: All

Ages: 15 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA I and II

Exclusion criteria

• Allergic to local anesthetic Open cholecystectomy History of chronic pain History of abdominal surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups

Intraperitoneal local anesthetic administration

Experimental group

Treatment:

Drug: Intraoperitoneal local anesthetic administration

Sub cutaneous local anesthetic administration

Active Comparator group

Treatment:

Drug: Sub cutaneous administration of local anesthetic