Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain

Sahlgrenska University Hospital

Status and phase: Completed; Phase 4

Conditions: Acute Coronary Syndromes

Treatments: Drug: Metoprolol; Drug: metoprolol plus morphine

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00718406

S203-02

Details and patient eligibility

About

The primary aim was to evaluate the relief of chest pain during the first 30 minutes among patients who received metoprolol alone as compared with metoprolol plus morphine

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute chest pain
• ECG-signs indicating myocardial ischemia

Exclusion criteria

• Heart rate < 60 beats/min
• Systolic blood pressure < 110 mmHg
• High degree AV-block
• Signs of obstructive pulmonary disease
• Signs of pulmonary oedema
• Unwillingness
• Participation in other studies
• Long delay between arrival of ambulance and randomisation

Trial design

0 participants in 2 patient groups

A

Active Comparator group

Description:

A=metoprolol

Treatment:

Drug: Metoprolol

B

Active Comparator group

Description:

B=metoprolol plus morphine

Treatment:

Drug: metoprolol plus morphine