Painful Post-Operative Hip Study

University of Wisconsin (UW)

Status and phase: Not yet enrolling; Phase 2

Conditions: Unilateral Hip Arthroscopy

Treatments: Combination Product: FDG PET/MRI

Study type: Interventional

Funder types: Other

Identifiers

NCT07066709

Protocol Version 6/6/2025 (Other Identifier)

A536110 (Other Identifier)

SMPH/ORTHO&REHAB/ORTHO (Other Identifier)

2025-0271

Details and patient eligibility

About

The goal of this clinical trial is to learn if the hips of people who undergo revision hip arthroscopy look different from the hips of people whose hip pain is resolved with the first hip arthroscopy and of people who choose the steroid injection for pain management.

Participants will complete one PET/MRI scan.

Full description

Hip arthroscopy utilization has increased significantly and, as such, people are now dealing with an increase in hip arthroscopy failures. In many cases, a failed hip arthroscopy is treated with a revision hip arthroscopy versus conversion to a total hip replacement, but these procedures may not adequately address the etiology of hip pain in the setting of a failed hip arthroscopy. Physicians need better diagnostic tools to appropriately diagnose post- hip arthroscopy hip pain, so that they can offer the appropriate treatment. The advent of FDG PET/MRI offers a highly sensitive imaging method that detects areas of abnormal inflammation. The sensitivity of this method exceeds that of other imaging modalities (e.g., MRI alone) and gives physicians the best possible chance of detecting abnormal inflammatory or hypermetabolic pathology. The ability to better diagnose pain sources around the articular joint with this unique approach has not yet been explored in the post-arthroscopic hip.

Enrollment: 15 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-45
• History of unilateral hip arthroscopy
• Does not have evidence of fracture, infection, or malignancy at 6 months post-hip arthroscopy
• Does not have evidence of depression or other major mental health conditions before the index hip arthroscopy
• Does not have persistent pain that requires opioid use, or does not have a history of opioid abuse
• Does not have any comorbidity results in systemic disease limiting function (ASA physical status classification >3)
• Not currently pregnant
• Presents with persistent pain (≥4/10 on NRS) for at least 6 months post-hip arthroscopy
• Undergo a revision hip arthroscopy with no surgical history on the contralateral limb

Exclusion criteria

• No unilateral hip arthroscopy
• Evidence of fracture, infection, or malignancy at 6 months post-hip arthroscopy
• Evidence of depression or other major mental health conditions before the index hip arthroscopy
• Has persistent pain that requires opioid use, or has a history of opioid abuse
• Has any comorbidity results in systemic disease limiting function (ASA physical status classification <3)
• Currently pregnant

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

Revision hip arthroscopy

Experimental group

Description:

Participants will have undergone a revision hip arthroscopy and will have a FDG PET/MRI

Treatment:

Combination Product: FDG PET/MRI