Pancreas Cancer Surveillance Using an Abbreviated MRI

Seoul National University

Status: Active, not recruiting

Conditions: Pancreas Cancer

Treatments: Diagnostic Test: Conventional follow-up; Diagnostic Test: Abbreviated PB MRI; Genetic: Gene mutation test

Study type: Interventional

Funder types: Other

Identifiers

NCT04592393

SNUH-2020-2950

Details and patient eligibility

About

This study aims to establish a prospective cohort of developing pancreas cancer and surveillance MRI protocol. With the focused surveillance protocol, we perform surveillance for pancreas cancer for five years to estimate the risk of pancreas cancer and the clinical feasibility of the surveillance MRI.

Enrollment: 200 patients

Sex: All

Ages: 50 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• On follow-up due to first degree-family history of PAC
• Or on follow-up for BD-IPMN (>= 2 cm) or main-duct type IPMN (> 5 mm)
• And signed informed consent

Exclusion criteria

• Contra-indication of performing MRI
• Not satisfying the selection criteria.
• Previously diagnosed with pancreatic malignancy
• Pregnancy or planning pregnancy

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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200 participants in 1 patient group

Abbreviated PB MRI

Experimental group

Description:

Short and Focused non-contrast MRI for surveillance

Treatment:

Genetic: Gene mutation test

Diagnostic Test: Conventional follow-up

Diagnostic Test: Abbreviated PB MRI