Pancreatic Cancer Registry: For Any Person With a Personal or Family History (NFPTR)

Johns Hopkins University

Status: Enrolling

Conditions: Pancreatic Cancer, ATM, BRCA, Hereditary Cancer

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT02886247

NA_00035453

P50CA062924 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The NFPTR was established in 1994 to find the causes of pancreatic cancer. In brief, the investigators are interested in both the genetic and non-genetic causes of pancreatic cancer. The investigators are particularly interested in finding the genes that cause pancreatic cancer to cluster in some families. Up to 10% of pancreatic cancer patients have another close relative who has also developed pancreatic cancer. This clustering of pancreatic cancers in families has yet to be explained; however, the investigators continue to identify new familial pancreatic cancer genes that explain this clustering in subsets of families. For example, in 2009 and 2012 the investigators discovered that mutations in the PALB2 and ATM genes jointly account up to 5% of the clustering of pancreatic cancer in families.

Enrollment: 12,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• personal or family history of pancreas tumors

Exclusion criteria

• none

Trial design

12,000 participants in 1 patient group

participants

Description:

individuals with a personal or family history of pancreas tumors