Pancreatic Cyst Fluid Glucose: New Armamentarium in the Diagnosis of Mucinous Pancreatic Cystic Lesion (CYST FLUID 01)

Asian Institute of Gastroenterology, India

Status: Not yet enrolling

Conditions: Pancreatic Cyst Fluid

Treatments: Diagnostic Test: non-cancerous cyst; Diagnostic Test: cancerous cyst.

Study type: Observational

Funder types: Other

Identifiers

NCT06189339

: pancreatic cyst glucose 1

Details and patient eligibility

About

Primary objectives

• To check for sensitivity and specificity of cystic fluid glucose level for differentiating the mucinous & non mucinous pancreatic cyst

Secondary Objectives:

comparison of cystic fluid tumor makers like CEA with cystic fluid glucose level. Check for cutoff value of cystic fluid glucose level for diagnosis of mucinous pancreatic cyst in Indian population.

Full description

For patients who have a pancreatic cyst bigger than 2cm found during a radiology exam, they will undergo an Endoscopic ultrasound exam to check the cyst and fluid will be collected for testing, including glucose, CEA (carcinoembryonic antigen), and amylase. A biopsy will be done if possible. We will analyze how well the glucose level in the fluid can tell us if the cyst is cancerous or not, using CEA level, EUS findings, and amylase level as the standard. This is an observational study, and patients will receive standard medical treatment. The study won't change the treatment they receive.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patients (between 18 to 60 years of age)

•Pancreatic cyst of size >2 cm noted on radiological imaging

Exclusion criteria

Patient's age <16yrs or >80 yrs. Prior history of pancreatitis (within 3 months) Pregnant female Unfit for endoscopic ultrasound Not wiling for consent

Trial design

30 participants in 2 patient groups

mucinous (malignant)

Description:

For patients who have a pancreatic cyst bigger than 2cm found during a radiology exam, they will undergo an Endoscopic ultrasound exam to check the cyst and fluid will be collected for testing, including glucose, CEA (carcinoembryonic antigen), and amylase. A biopsy will be done if possible. We will analyze how well the glucose level in the fluid can tell us if the cyst is cancerous or not, using CEA level, EUS findings, and amylase level as the standard. This is an observational study, and patients will receive standard medical treatment

Treatment:

Diagnostic Test: non-cancerous cyst

non mucinous (Non-malignant) pancreatic cyst.

Description:

For patients who have a pancreatic cyst bigger than 2cm found during a radiology exam, they will undergo an Endoscopic ultrasound exam to check the cyst and fluid will be collected for testing, including glucose, CEA (carcinoembryonic antigen), and amylase. A biopsy will be done if possible. We will analyze how well the glucose level in the fluid can tell us if the cyst is cancerous or not, using CEA level, EUS findings, and amylase level as the standard. This is an observational study, and patients will receive standard medical treatment

Treatment:

Diagnostic Test: cancerous cyst.