Para-vertebral Dexmedetomidine and the Incidence of Postoperative Chronic Pain

Assiut University

Status: Completed

Conditions: Pain, Postoperative

Treatments: Drug: Dexmedetomidine; Drug: Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT03632161

IRB00009920

Details and patient eligibility

About

Up to our knowledge there is no study focused upon the incidence of post VATS chronic pain when dexmedetomidine is used.

Full description

Most Video-Assisted Throcoscopy Surgery (VATS) procedures are considered low-risk interventions requiring short hospital stays or even outpatient settings. Because of these factors, VATS did not raise as much interest as thoracotomy in its postoperative pain management. However, it is a fact that pain following VATS can be severe and long-lasting .According to Richardson and colleagues, 38% of VATS procedures present persistent pain two months after surgery as a result of acute nerve damage during the surgical procedure.

Enrollment: 60 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA II-III
• Adult
• Video-assisted thoracic surgery

Exclusion criteria

• Patient refusal
• Allergy to medication
• Coagulopathy
• Malformation

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Dexmedetomidine

Active Comparator group

Description:

Dexmedetomidine is added to bupivacaine the paravertebral block

Treatment:

Drug: Dexmedetomidine

Bupivacaine

Other group

Description:

Bupivacaine only in the paravertebral block

Treatment:

Drug: Bupivacaine