Paraesternal Blockade and Lactate Serum Levels in Patients with Cardiac Surgery.

Instituto Mexicano del Seguro Social

Status and phase: Completed; Phase 3

Conditions: Cardiac Surgery; Parasternal Block; Serum Lactate

Treatments: Diagnostic Test: Lactate serum level; Procedure: parasternal block

Study type: Interventional

Funder types: Other

Identifiers

NCT06608290

R-2023-1301-024.

Details and patient eligibility

About

Parasternal blockade has been related to a reduction of the postoperative inflammatory response, by inhibition of the stress response, leading to a better prognosis. Increased lactate level is a useful parameter in identifying patients at risk of postoperative morbidity and mortality. The objective was to evaluate the association between parasternal blockade and serum lactate level in patients undergoing cardiac surgery, both trans- and post-anesthesia. 86 patients between 60-70 years of age participated. An association was found between the application of parasternal blockade in cardiac surgery and the presence of lower trans and postanesthetic serum lactate levels.

Full description

An analytical cross-sectional study in adult patients who underwent elective cardiac surgery. A total sample of 86 patients was obtained, 43 in the case group and 43 in the control group. Adult patients older than 18 years, of either sex, with ASA II-III, patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass were included.

Enrollment: 86 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria

• Adult patients over 18 years of age
• Either sex
• ASA II-IV
• Patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass.

Elimination criteria

• Patients with pre-existing conditions that could independently affect serum lactate levels

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

86 participants in 2 patient groups

Blockade

Experimental group

Description:

In patients which parasternal block has been applied

Treatment:

Procedure: parasternal block

Diagnostic Test: Lactate serum level

Control

Experimental group

Description:

In patients which parasternal block has not been applied

Treatment:

Diagnostic Test: Lactate serum level