Parathyroid Cancer Versus Atypical Parathyroid Neoplasm; Investigating Their Clinical Characteristics and Biological Behavior

M.D. Anderson Cancer Center

Status: Completed

Conditions: Parathyroid Carcinoma; Parathyroid Neoplasm

Treatments: Other: Chart Review

Study type: Observational

Funder types: Other

Identifiers

NCT03046524

PA15-0808

Details and patient eligibility

About

Objectives:

1. Identify the clinical characteristics of parathyroid (PTH) cancer and PTH atypical neoplasms
2. Investigate if PTH carcinoma and atypical neoplasm present a biological behaviour and have a different impact on the health of the patients

Full description

Data between the years of 1/1/2002 and 12/31/2013 will be analyzed. The medical records of all adult patients that had a parathyroidectomy for primary PHPT in MD Anderson Cancer Center will be screened in order to identify patients that had a histopathological diagnosis of parathyroid carcinoma or atypical parathyroid neoplasm.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients from MDACC diagnosed with PHPT that have a histopathological diagnosis of PTH carcinoma or atypical parathyroid neoplasm between the years 1/1/2002 and 12/31/2013

Exclusion criteria

• Pediatric patients
• Cases with incomplete records
• Patients where the follow-up will be less than six months

Trial design

100 participants in 2 patient groups

Parathyroid Carcinoma

Description:

Charts from participants with histopathological diagnosis of parathyroid carcinoma.

Treatment:

Other: Chart Review

Atypical Parathyroid Neoplasm

Description:

Charts from participants with parathyroid tumors with some atypical features found in parathyroid carcinoma, but not enough histologic criteria to make the diagnosis of parathyroid carcinoma.

Treatment:

Other: Chart Review