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Paravertebral Block Versus Erector Spinae Plain Block In Percutaneous Nephrolithotomy

N

Nazmy Edward Seif

Status

Completed

Conditions

Renal Stone
Analgesia
Nephrolithiasis
Anesthesia

Treatments

Procedure: Erector Spinae Plain Block
Procedure: Paravertebral Block

Study type

Interventional

Funder types

Other

Identifiers

NCT04998435
PVBVESPBPCNL

Details and patient eligibility

About

Nowadays, Percutaneous Nephrolithotomy (PCNL) has been the surgical procedure of choice for renal stones larger than 2cm or staghorn stones. Yet, the associated postoperative pain is a major drawback. The regional anesthetic management of pain in PCNL operation has been of great concern. The introduction of ultrasound guided erector spinae plane block and paravertebral plane block has been under great focus regarding the efficacy of postoperative pain management. Paravertebral plane block (PVB) is a regional nerve block technique that depends on local anesthetic injection adjacent to the vertebra to block spinal nerve roots in a dermatomal distribution. Erector spinae plane block (ESPB) is a newer regional anesthesia technique that depends on injecting local anesthetic (LA) in a plane between the transverse process and erector spinae muscle. The LA diffuses into the paravertebral space and spreads on both rami (dorsal and ventral) of spinal nerves through spaces between adjoining vertebrae.

The aim of this study is to compare the effect of ultrasound guided Paravertebral blockade versus Erector spinae blockade on postoperative opioid use as well as postoperative pain control in patients undergoing unilateral PCNL.

Enrollment

50 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • ASA I - II.
  • Patients undergoing unilateral percutaneous nephrolithotomy (PCNL) surgery under general anesthesia.

Exclusion criteria

  • Patient refusal.
  • Uncooperative patients.
  • Allergy to local anesthetics.
  • Infection or anatomical abnormality at injection site.
  • Coagulopathy.
  • Bilateral PCNL.
  • Spinal anesthesia or any other regional anesthesia.
  • Block failure: the block will be considered a failed block if the patient requires more than two doses of rescue analgesia in the first hour postoperatively.

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

50 participants in 2 patient groups

ESPB group
Active Comparator group
Description:
Erector Spinae Plain Block
Treatment:
Procedure: Erector Spinae Plain Block
PV group
Active Comparator group
Description:
Paravertebral Block
Treatment:
Procedure: Paravertebral Block

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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