Paravertebral Block vs no Block in Open Pancreaticoduodenectomy

Mayo Clinic

Status and phase: Terminated; Phase 4

Conditions: Pancreaticoduodenectomy

Treatments: Drug: Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05820997

22-012297

Details and patient eligibility

About

The purpose of this study is to compare intra and postoperative pain control between Paravertebral block vs no block in open pancreaticoduodenectomy. Length of stay, and complications will also be recorded. For this study the investigator plans to randomize to obtain objective data for clinical decisions and improve patient outcomes. Following surgery patients in both groups, data will be collected from the first 48 hours after surgery and at discharge.

Enrollment: 2 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients willing and have signed consent.
• Nonpregnant adults undergoing open pancreaticoduodenectomy via standard upper midline incision without contraindications to para vertebral block (PVB)

Exclusion criteria

• Not able or unwilling to sign consent.
• Currently pregnant or lactating.
• Patients with chronic pain, requiring daily opiate use at time of surgery.
• Patients intolerant of opiates, NSAIDS, acetaminophen or local anesthetics.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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2 participants in 2 patient groups

Paravertebral Block Pre Procedure

Active Comparator group

Description:

Subject will receive a preoperative paravertebral block only

Treatment:

Drug: Ropivacaine

No Paravertebral Block

No Intervention group

Description:

Subject will receive no paravertebral block.