ParKinWalk: Physical Activity and Long Group-walking for Parkinson's Disease (ParKInWalk)

Università degli Studi di Brescia

Status: Completed

Conditions: Parkinson Disease; Healthy Aging

Treatments: Other: Exercise program followed by long walk in group; Other: Exercise program followed by long walk in group (controls)

Study type: Interventional

Funder types: Other

Identifiers

NCT04266782

19/03

Details and patient eligibility

About

The study will evaluate the impact of exercise training program followed by long-walking onon supervised and unsupervised gait assessment in Parkinson´s disease and control subjects.

Full description

Background: Several studies suggest an impact of physical exercise on walking parameters in Parkinson´s disease (PD) patients.

Objective: the present study will evaluate the impact of three months physical exercise training program followed by a group-long walking on motor impairment in PD.

Methods:

PD patients will be randomized in two arms: one group will be assessed to a training exercise program of three months followed by long-walking in group under the support of physician/physiotherapist and caregivers. A complete motor, cognitive and general assessment will be performed at baseline. The patients will be evaluated under supervised an unsupervised conditions at baseline, before the long-walking, during the walking and after 2 months after the walk.

Enrollment: 40 patients

Sex: All

Ages: 30 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Parkinson´s disease diagnosis
• stable dopaminergic treatment ( stable dose in the last three months before baseline evaluation)

Exclusion criteria

• gait impairment due to other medical conditions
• dementia
• impulsive compulsive disorder
• severe depression

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 3 patient groups

Physical exercise program and Long-walking

Experimental group

Description:

A physical training will be started three months before the long-walking. The subjects will have to walk for at least 3 hours per week up to 6 hours per week during the training. THe long-distance capacity will be verified in 3 different one-day walking of 10, 15 and 18 Km before the long-walking performance. The long-walking will be organized with the support of a physician, study nurse, physiotherapy with car support in case of need. The subject are request to complete the walk of 104 Km of Portuguese route of Santiago de Compostela walk.

Treatment:

Other: Exercise program followed by long walk in group

Usual care

No Intervention group

Description:

The subjects will be followed according to current standard.

Control group-intervention

Active Comparator group

Description:

A physical training will be started three months before the long-walking. The subjects will have to walk for at least 3 hours per week up to 6 hours per week during the training. THe long-distance capacity will be verified in 3 different one-day walking of 10, 15 and 18 Km before the long-walking performance. The long-walking will be organized with the support of a physician, study nurse, physiotherapy with car support in case of need. The subject are request to complete the walk of 104 Km of Portuguese route of Santiago de Compostela walk.

Treatment:

Other: Exercise program followed by long walk in group (controls)