Paroxysmal Positional Vertigo & Repositioning Maneuvers

Neuro Counsel Hospital, Pakistan

Status: Completed

Conditions: Benign Paroxysmal Positional Vertigo

Treatments: Other: betahistine & Modified eply & Semont maneuver; Other: Modified eply & Semont maneuver

Study type: Interventional

Funder types: Other

Identifiers

NCT05309538

336

Details and patient eligibility

About

: Benign Paroxysmal Positional Vertigo is a condition related to vestibular system accompanied by dizziness, tinnitus and balance problems leading to increased fall risk and potential disability. Various treatment options are available including pharmacotherapy and vestibular rehabilitation with varied results

Full description

Objective: The objective of this study was to compare the efficacy of Modified Epley & Semont's maneuver with and without Betahistine for BPPV Material & Methods: The study was a single blind randomized control trail. Total number of patients were 97 as calculated by Epitool calculator. Duration of the study was of one year from 2 January 2021 to 1st January 2022. Out of a total 97 patients, 90 met the inclusion criteria. These participants were randomized by lottery method into two equal groups. Group A (control group) was receiving both maneuvers only while group B (experimental group) included participants receiving betahistine along with both maneuvers. The impact of dizziness and quality of life was measured through EQ-5D-5L questionnaire and dizziness handicap inventory (DHI) in order to analyze the effectiveness of treatments. Pre and Post treatment results were compared within group by Wilcoxon rank test and for between groups, Mann Whitney U test was performed

Enrollment: 90 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age between 18-60
• positive modified Dix Hil pike test
• repetitive vertigo spells affecting activities of daily livings (ADLs)

Exclusion criteria

• any cervical spine problem
• vertigo due to central disease
• tumors
• systemic disease
• cardiac disease
• Parkinson disease
• bed bound patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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90 participants in 2 patient groups

Group A

Active Comparator group

Description:

Control group

Treatment:

Other: Modified eply & Semont maneuver

group B

Experimental group

Description:

experimental group

Treatment:

Other: betahistine & Modified eply & Semont maneuver