PARTial BREast RECONstruction With Chest Wall Perforator Flap (PartBreCon)

NHS Foundation Trust

Status: Enrolling

Conditions: Breast Reconstruction Surgery; Breast Cancer Early Stage Breast Cancer (Stage 1-3); Breast Surgery; Breast Neoplasms; Breast Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT06728527

ID5342

Details and patient eligibility

About

The goal of this observational study is to ascertain the outcomes following partial breast reconstruction using chest wall perforator flaps after breast conservation surgery.

Full description

The Main Outcomes and Measures are:

A) Patient Demographics and Tumour characteristics

1. Patient demographics: age, body mass index (BMI), comorbidities
2. Preoperative tumour characteristics and location influencing surgical planning

B) Treatment characteristics

1. Surgical: operative data, including flap types and distribution
2. Oncological: systemic therapies (adjuvant and neoadjuvant), radiotherapy

Enrollment: 1,001 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing partial breast reconstruction using CWPF for primary breast cancer
• Delayed correction of breast deformity following previous BCS
• Each surgeon is to have performed a minimum of 10 CWPFs
• Each centre anticipates completing a minimum of 10/year

Exclusion criteria

• Patients undergoing volume displacement BCS
• Patients undergoing mastectomy +/- immediate breast reconstruction

Trial design