Partial Posterior Hyaloidectomy in Macular Surgery

Samsung Medical Center

Status and phase: Completed; Phase 1

Conditions: Retinal Detachment; Retinal Break

Treatments: Procedure: Partial posterior hyaloidectomy (a modified procedure of vitrectomy)

Study type: Interventional

Funder types: Other

Identifiers

NCT01454466

2011-05-011

Details and patient eligibility

About

To evaluate the effect of partial posterior hyaloidectomy on preventing iatrogenic retinal breaks related to induction of a posterior vitreous detachment

Full description

The induction of a posterior vitreous detachment (IPVD) during vitrectomy have been suggested as one of the etiologies of iatrogenic retinal break related to vitrectomy.The iatrogenic retinal breaks related to IPVD usually develop near or anterior to the equatorial region.

Thus, the investigators hypothesized that this complication could be prevented by restricting the extent of IPVD, and planned a modified procedure of vitrectomy in which the extent of IPVD and removal of vitreous cortex was restricted to about slightly beyond the margin of temporal major vascular arcade.

The investigators have termed this procedure, partial posterior hyaloidectomy. Unlike RRD or proliferative diabetic retinopathy, lesions are localized within the major vascular arcade in macular disorders so that macular disorders could be an eligible indication for this procedure.

Enrollment: 50 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cases of idiopathic ERM or idiopathic MH without evidence of PVD preoperatively

Exclusion criteria

• history of previous intraocular surgery

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)