Partial Wave Spectroscopic Detection of Colon Cancer Risk (Brushings)

The University of Chicago

Status: Completed

Conditions: Colon Cancer; Ulcerative Colitis

Treatments: Procedure: PWS Testing

Study type: Observational

Funder types: Other

Identifiers

NCT01095432

10-066-B

Details and patient eligibility

About

The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS) in patients who will undergo a standard of care colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC).

Full description

The purpose of this study is to study samples of rectal mucosa (the moist lining of the rectum) using a new light scattering technology, called partial wave spectroscopy (PWS)in patients who will undergo a colonoscopy or a flexible sigmoidoscopy and have a history of ulcerative colitis (UC). PWS has been recently developed to allow scientists to learn about any changes to the cells that may indicate a risk of developing colon cancer. We believe that the PWS test will more accurately detect the risk of colon cancer.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient must be 18 years old or older.
• Patient is already scheduled for a standard of care colonoscopy or flexible sigmoidoscopy.
• Patient has not received chemotherapy.
• History of ulcerative colitis.

Exclusion criteria

• Patient is unable to give informed consent..
• Patient has received chemo or radiation therapy within the past 3 months.

Trial design

40 participants in 1 patient group

Main Study Group

Description:

All subjects who are undergoing a standard of care colonoscopy for flexible sigmoidoscopy and have a history of UC and agree to participate will be in the main study group.

Treatment:

Procedure: PWS Testing