Passive Transmission of COVID-19 Antibody From Mother to Infant

Chongqing Medical University

Status: Enrolling

Conditions: Passive Transmission of Maternal and Infant Antibodies

Treatments: Biological: sars-cov-2 vaccine or infection

Study type: Observational

Funder types: Other

Identifiers

NCT05851911

2022-380

Details and patient eligibility

About

At present, there is no relevant research focusing on children's acquisition of novel coronavirus antibodies through maternal passive transmission. Therefore, this study assessed the changes of maternal passive transmission of COVID-19 antibodies by monitoring the specific antibodies of COVID-19 in young children; This will lay a foundation for further exploring the risk of COVID-19 infection in children and formulating immune prevention strategies.

Enrollment: 300 estimated patients

Sex: All

Ages: Under 2 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Children aged 0-2;
2. No history of blood transfusion, chemotherapy, or related immunosuppressive therapy; No immune system related diseases;

Exclusion criteria

Not willing to participate

Trial design

300 participants in 4 patient groups

Control group 1

Description:

Mother not vaccinated with COVID-19 vaccine

Treatment:

Biological: sars-cov-2 vaccine or infection

Control group 2

Description:

The mother was vaccinated with COVID-19 vaccine before pregnancy, and was not infected during pregnancy

Treatment:

Biological: sars-cov-2 vaccine or infection

Control group 3

Description:

The mother was vaccinated with COVID-19 vaccine before pregnancy, and was infected during pregnancy

Treatment:

Biological: sars-cov-2 vaccine or infection

Experimental group

Description:

The mother was not vaccinated with COVID-19 vaccine before pregnancy, so she was infected during pregnancy

Treatment:

Biological: sars-cov-2 vaccine or infection