Pathogen Detection in Infectious Uveitis

Shanghai Jiao Tong University

Status: Unknown

Conditions: Infectious Panuveitis; Infectious Iridocyclitis

Study type: Observational

Funder types: Other

Identifiers

NCT04521673

XH-20-014

Details and patient eligibility

About

Infectious uveitis is a very important blinding disease. Some people who have been diagnosed with idiopathic uveitis may also have the activity of pathogens in the eye. However, due to the limitation of the amount of ocular samples, it is difficult to make a rapid and effective diagnosis of infection.Current study is to explore the infective cause of uveitis in China by using a broad diagnostic approach of detection.

Full description

Infectious uveitis is a very important blinding disease. Some people who have been diagnosed with idiopathic uveitis may also have the activity of pathogens in the eye. However, due to the limitation of the amount of ocular samples, it is difficult to make a rapid and effective diagnosis of infection.

The study is to explore the infective cause of uveitis in China by using a broad diagnostic approach of detection, including multiple molecular bio-techniques. We also plan to explore the distribution of pathogens in infectious uveitis.

Enrollment: 100 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patient at a referal hospital eye clinic with clinically suspected infectious uveitis

Exclusion criteria

• Patients not eligible for the Inclusion Criteria
• Confirmed auto-immune uveitis

Trial design

100 participants in 2 patient groups

infectious uveitis

Description:

Patients suffering from suspected infectious uveitis, who have vitrectomy performed for diagnostic purpose or anterior chamber tap

Control group

Description:

Patients suffering from either cataract surgery or vitrectomy who has been ruled out for infectious ocular diseases