Pathogenic Species and Genotypes of Bacterial Diversity in Relation to the Severity of Dental Caries (Caries Species)

Centre Hospitalier Universitaire de Nīmes

Status: Completed

Conditions: Dental Cavity

Treatments: Biological: Saliva sampling; Other: Dental cavity evaluation; Biological: Plaque sampling

Study type: Observational

Funder types: Other

Identifiers

NCT02056262

2013-A01213-42 (Other Identifier)

AOI/2012/LH

Details and patient eligibility

About

The primary objective of this study is to estimate the distribution of pathogenic species and genotypes of bacterial diversity in 7 stages ICDAS (International Caries Detection and Assessment System) corresponding to the severity of dental caries among patients aged 3-45 years consulting in the Dentistry Departments of the Nîmes University Hospital and the Montpellier University Hospital.

Full description

Secondary objectives include:

• Compare the distribution of bacterial species in relation to stages of severity of caries
• Compare the results from plaque with those of saliva samples.

Enrollment: 56 patients

Sex: All

Ages: 3 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Volunteers aged 3 to 45 who come in to the hospital for a dental consultation
• Minors must have parental permission
• The patient must have given his/her informed and signed consent

Exclusion criteria

• The patient is participating in another study
• The patient is in an exclusion period determined by a previous study
• The patient is pregnant, or breastfeeding
• The patient has been on antibiotics within the past two months
• Smokers
• Teeth under current care
• Parodontopathy
• Use of a mouthwash within the last week
• Insufficient numbers of healthy and/or teeth with carious lesions for carrying out the study

Trial design

56 participants in 2 patient groups

3 to 16 years of age

Description:

Volunteers of 3 to 16 years of age, coming in to the hospital for a dental consultation. See inclusion/exclusion criteria. Intervention: Dental cavity evaluation Intervention: Saliva sampling Intervention: Plaque sampling

Treatment:

Other: Dental cavity evaluation

Biological: Plaque sampling

Biological: Saliva sampling

17 - 45 years of age

Description:

Volunteers of 17 to 45 years of age, coming in to the hospital for a dental consultation. See inclusion/exclusion criteria. Intervention: Dental cavity evaluation Intervention: Saliva sampling Intervention: Plaque sampling

Treatment:

Other: Dental cavity evaluation

Biological: Plaque sampling

Biological: Saliva sampling