Pathophysiological Explorations of Red Blood Cells (GR-Ex)

Imagine Institute

Status: Enrolling

Conditions: Red Blood Cell Disorder

Treatments: Other: Biological sampling

Study type: Observational

Funder types: Other

Identifiers

NCT03541525

IMNIS2015-04

Details and patient eligibility

About

GR-Ex is a program labelled by Labex (Laboratory of Excellence) by the French Ministry of Higher Education and Research. This program aims to develop the means to improve knowledge in the physiology and pathologies of erythropoiesis, red blood cells and iron metabolism, and to develop new therapeutic protocols capable of providing added value in terms of innovation.

Enrollment: 3,750 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• To be affected or have a family history of disease bound to the red blood cell,
• For adult subjects, have signed an informed consent form,
• For minor or major under legal safeguard subjects, the form must be signed by both parents (for minors) or by the legal representative,
• Be affiliated to health insurance.

Exclusion criteria

• Being deprived of freedom

Trial design

3,750 participants in 2 patient groups

Affected patients

Description:

Biological samples of blood for all patients. Biological samples of saliva, surgical remainder (skin, tumor, kidney,....), saliva, urine, hair.

Treatment:

Other: Biological sampling

Non affected relatives

Description:

Biological samples of blood for all relatives.

Treatment:

Other: Biological sampling