Patient Controlled Regional Analgesia Following Carpal Tunnel Release: A Double-Blind Study Using Distal Perineural Catheters

Region Örebro County

Status and phase: Completed; Phase 4

Conditions: Carpal Tunnel Syndrome

Treatments: Drug: Ropivacaine 0.2%; Drug: Normal saline; Drug: Ropivacaine 0.75%

Study type: Interventional

Funder types: Other

Identifiers

NCT00678314

LMV 151:2003/9759

Details and patient eligibility

About

This study was done with the primary aim of assessing the efficacy (as calculated by pain intensity difference) of patient controlled regional analgesia (PCRA) technique against oral analgesics, which has been the standard of care at our hospital. Secondary objectives were to analyze the volume and dose of LA that should be given, patient satisfaction and the long-term outcome for patients treated with the PCRA technique.

Enrollment: 88 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with clinically established carpel tunnel syndrome
• Surgery performed under local anesthesia

Exclusion criteria

• Chronic pain requiring analgesics

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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88 participants in 3 patient groups, including a placebo group

Group A

Active Comparator group

Treatment:

Drug: Ropivacaine 0.2%

Group B

Active Comparator group

Treatment:

Drug: Ropivacaine 0.75%

Group C

Placebo Comparator group

Treatment:

Drug: Normal saline